| Date | OPP | Time / TV | Venue |
|---|---|---|---|
| Nov 3, 2026 | vs | Cameron Indoor Stadium | |
| Nov 8, 2026 | @ | American Airlines Center | |
| Nov 12, 2026 | @ | Joseph G. Echols Memorial Hall | |
| Nov 15, 2026 | vs | Cameron Indoor Stadium | |
| Nov 19, 2026 | vs | Cameron Indoor Stadium | |
| Nov 21, 2026 | @ | Francis S. Levien Gymnasium | |
| Nov 28, 2026 | @ | TD Garden | |
| Dec 3, 2026 | vs | Cameron Indoor Stadium | |
| Dec 6, 2026 | vs | Cameron Indoor Stadium | |
| Dec 16, 2026 | @ | Mortgage Matchup Center | |
| Dec 19, 2026 | @ | Michelob Ultra Arena | |
| Dec 20, 2026 | @ | 10:00 pm
ESPN
| Michelob Ultra Arena |
| Dec 28, 2026 | vs | Cameron Indoor Stadium | |
| Dec 31, 2026 | @ | John Paul Jones Arena | |
| Jan 3, 2027 | @ | William Neal Reynolds Coliseum | |
| Jan 10, 2027 | @ | Purcell Pavilion at the Joyce Center | |
| Jan 14, 2027 | vs | Cameron Indoor Stadium | |
| Jan 17, 2027 | vs | Cameron Indoor Stadium | |
| Jan 21, 2027 | @ | Silvio O. Conte Forum | |
| Jan 24, 2027 | vs | Cameron Indoor Stadium | |
| Jan 28, 2027 | @ | Donald L. Tucker Center | |
| Jan 31, 2027 | @ | Carmichael Arena | |
| Feb 7, 2027 | vs | Cameron Indoor Stadium | |
| Feb 11, 2027 | @ | McCamish Pavilion | |
| Feb 14, 2027 | vs | Cameron Indoor Stadium | |
| Feb 18, 2027 | vs | Cameron Indoor Stadium | |
| Feb 21, 2027 | @ | LJVM Coliseum | |
| Feb 25, 2027 | @ | Moody Coliseum | |
| Feb 28, 2027 | vs | Cameron Indoor Stadium |
Duke Blue Devils
- 27-9
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