Wednesday, October 21, 2026
| Home | Away | Result |
|---|---|---|
Puebla
| 
Monterrey
|
PUE 1 - 4 MTY
|
Atlas
| 
America
|
ATS 2 - 5 CFA
|
Toluca
| 
Tijuana
|
TOL 2 - 2 CTJ
|
Santos Laguna
| 
Pumas UNAM
|
CSL 2 - 0 PUM
|
Pachuca
| 
Cruz Azul
|
PAC 1 - 2 CAZ
|
Notes
- All times are US/Eastern.