Diamondbacks starter Wade Miley endured a rough outing as he suffered his first loss of the season Friday night against the Padres.

Miley, who made his sixth start of the season, surrendered two runs in the second frame and served up a two-run home run to Yonder Alonso in the fifth. It was Miley's first home run allowed since his season debut on April 5. The left-hander was charged with four runs on nine hits over five innings of work in a 7-6 defeat. He struck out four and walked three in 97 pitches, 63 strikes.

Miley has walked 10 and struck out seven in his last 9 1/3 innings of work. He will try to get back on track Wednesday on the road against the Dodgers. He is 2-0 with a 2.11 ERA in his last three starts at Dodger Stadium.