The Twins activated third baseman Trevor Plouffe, who had been on paternity leave, and pitcher Kevin Jepsen, who was acquired in a trade-deadline deal with Tampa Bay.
To make room, the team optioned shortstop Danny Santana to Triple-A Rochester and shortstop Jorge Polanco to Double-A Chattanooga, per MLB.com.
Santana was hitting .219 with the Twins this season. Polanco hit .429 in three games.