Mariners vs. Tigers prediction, odds, time: 2025 MLB playoff betting picks for ALDS Game 4 by proven model
SportsLine's model simulated Seattle vs. Detroit 10,000 times and revealed its MLB picks for Wednesday's American League Division Series Game 4 matchup at Comerica Park in Detroit
The Seattle Mariners will look to close out their best-of-five American League Division Series with the Detroit Tigers when they meet in Game 4 on Wednesday. Seattle took a 2-1 series lead with an 8-4 win on Tuesday. The Mariners (90-72), who won the AL West, are looking to reach the ALCS for the first time since 2001. The Tigers (87-75), who finished second in the AL Central, last reached the ALCS in 2013. The winner of this series will then face the Blue Jays vs. Yankees winner in the American League Conference Series.
First pitch from Comerica Park in Detroit is set for 3:08 p.m. ET. The Mariners have won six of the past seven meetings with the Tigers. Seattle is a -111 favorite on the money line (risk $111 to win $100) in the latest Mariners vs. Tigers odds from DraftKings Sportsbook, with Detroit at -108. The total number of runs Vegas thinks will be scored, or the over-under, is 8.5. Before making any Mariners vs. Tigers picks, be sure to be sure to see the MLB predictions and betting advice from SportsLine's proven computer model.
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The SportsLine Projection Model simulates every MLB game 10,000 times. It enters the second week of the 2025 MLB playoffs a profitable 35-29 on top-rated MLB money-line picks this season. It has excelled making home run prop picks this season, returning nearly 30 units of profit. Anybody following its MLB betting picks at sportsbooks and on betting sites could have seen strong returns.
Now, the model has set its sights on Mariners vs. Tigers and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Tigers vs. Mariners:
Mariners vs. Tigers money line | Seattle -111, Detroit -108 at DraftKings Sportsbook |
Mariners vs. Tigers over/under | 8.5 runs |
Mariners vs. Tigers run line | Seattle -1.5 (+151) |
Mariners vs. Tigers picks | |
Mariners vs. Tigers streaming | Fubo (Try for free) |
Why the Tigers can win
Right-hander Casey Mize (14-6, 3.87 ERA) is expected to get the start for Detroit. In 28 games, all starts, he has logged 149 innings pitched, allowing 153 hits and 36 walks, while striking out 139. He received a no-decision in a 6-1 loss to the Cleveland Guardians in Game 2 of the AL Wild Card on Oct. 1. He has won five of his last seven decisions, and was 1-1 against Seattle during the regular season.
Left fielder Riley Greene has been among Detroit's top hitters this postseason, batting .261 through six games. During the regular season, Greene hit .258 with 31 doubles, one triple, 36 homers, 111 RBI and 84 runs scored. In a 3-2 11-inning win over Seattle in the ALDS opener, Greene was 2-for-5. He was also 2-for-5 with an RBI in a Game 3 win over the Guardians in the Wild Card round. See which team to back at SportsLine.
Why the Mariners can win
Seattle is expected to send right-hander Bryce Miller (4-6, 5.68 ERA) to the mound. In 18 starts this season, Miller logged 90.1 innings, allowing 93 hits, 57 earned runs and 34 walks with 74 strikeouts. He has won two of his last three decisions, including a 4-2 win at Cleveland on Aug. 31. In that game, he pitched six innings, allowing two hits, two earned runs and one walk with three strikeouts. He was 12-8 with a 2.94 ERA in 31 starts during the 2024 season.
Catcher Cal Raleigh has been red hot this series. Through three games, Raleigh is hitting .462 with one double, one home run and three RBI. During the regular season, Raleigh played in 159 games, batting .247 with 24 doubles, 60 homers and 125 RBI with 110 runs scored. In the series opener against Detroit, he was 3-for-5. He doubled in the 3-2 win over the Tigers in Game 2. See which team to back at SportsLine.
How to make Mariners vs. Tigers picks
SportsLine's model is leaning Over on the total, projecting 8.6 combined runs. Tt says one side of the money line has all the value. You can head to SportsLine to see the model's MLB picks.
So who wins Mariners vs. Tigers, and which side of the money line has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.
