Brewers closer John Axford endured another rough outing Wednesday night against the Rockies.

After blowing the save on opening day, he allowed three runs on five hits over two-thirds of an inning.

The right-hander came on in the ninth with his team trailing by one and gave up a leadoff single before Michael Cuddyer hit a two-run homer. Axford surrendered a solo home run to Dexter Fowler and was pulled after throwing 18 pitches, 11 for strikes.

Axford has a 21.60 ERA through two appearances while getting tagged with three home runs.