Joe Mauer and Kennys Vargas swapped positions for the Twins on Saturday. Mauer, who has started 14 of the team's 16 games at first base, will play designated hitter. Vargas, who has been the DH for 13 games, will play first.
It's the second start at first base this season for Vargas and Mauer's third time at DH.
The Twins are +145 money line underdogs at Seattle.