Jefferson and most other starters aren't expected to play in Saturday's preseason game against the Browns, Mark Craig of The Star Tribune reports.
It sounds like the Vikings will use fewer key players than they did in their preseason opener, although Jefferson was also held out for that one. He's set to open the season with Sam Darnold as his starting QB after J.J. McCarthy's season-ending meniscus surgery put an end to any thoughts of a job battle.