Pierre (calf) has been ruled out for Sunday's game against the Lions, Brooke Pryor of ESPN.com reports.
Pierre will end up missing a second straight game due to a calf injury that he likely picked up during the Steelers' Week 14 win over the Ravens. Asante Samuel -- who intercepted Tua Tagovailoa during Pittsburgh's Week 15 victory over Miami -- will likely start at outside corner opposite Joey Porter on Sunday in Pierre's absence.