Williams (hamstring) could miss Sunday's game against the Packers, Adam Schefter of ESPN reports.
Williams tweaked his hamstring in Monday's victory over the Panthers and head coach Dennis Allen suggested Tuesday the running back would miss "some time", although how much time remains unclear. Kendre Miller (hamstring), Tony Jones and the versatile Taysom Hill are all candidates to see more work in the backfield if Williams is indeed sidelined. Alvin Kamara (suspension) will also return in Week 4 and should immediately move into the top spot on the depth chart.