Kamara sustained a knee injury during Sunday's game versus the Falcons.
Kamara was twisted to the turf awkwardly on a tackle in the first half, after which he visited the medical tent multiple times before going to the locker room. He combined for five touches for 15 yards from scrimmage prior to his departure. Devin Neal will take over the No. 1 RB role for as long as Kamara is sidelined.