Madubuike (neck) has been ruled out ahead of Sunday's game against the Colts, Jamison Hensley of ESPN.com reports.
Madubuike logged a limited practice session all three days this week. The defensive tackle is close to returning from a severe neck injury he suffered last September but will need to be fully cleared before he can return to the field. With the 28-year-old unable to suit up, Aeneas Peebles will likely draw the start at tackle next to Travis Jones and Calais Campbell on Sunday.