McDonald (knee) did not practice Wednesday, Rich Cimini of ESPN.com reports.
McDonald may have injured his knee during the Jets' Week 16 loss to the Saints, when he played 65 snaps (57 on defense, eight on special teams) and finished with four tackles (three solo), including 1.0 sacks. He'll have two more chances to log a full practice and avoid an injury designation ahead of Sunday's AFC East tilt against the Patriots.