Agnew had two carries for minus-2 yards, returned one kickoff for 20 yards and returned two punts for 58 yards during Sunday's 31-21 win against the Colts.
The 28-year-old played just five offensive snaps as Christian Kirk, Calvin Ridley and Zay Jones dominated the playing time among Jacksonville's wideouts. Agnew delivered a 48-yard punt return during the fourth quarter to help set up a Jaguars touchdown, but he's unlikely to have much of an offensive role beyond gadget plays while the aforementioned trio remains healthy.