Barkley (ankle) has been ruled out for Sunday's game against Carolina, Zack Rosenblatt of The Newark Star-Ledger reports.
While Barkley was out last week, Devontae Booker took on a 72-percent snap share and 16 touches in a 38-11 loss to the Rams. Though he hasn't yet returned to practice since suffering a sprained left ankle, Barkley will have an extra day on the schedule to help him try to avoid a third straight absence, with the Giants facing the Chiefs on "Monday Night Football" in Week 8.