Barkley (ankle) has been ruled out for Sunday's game against the Rams.
Barkley hasn't been placed on IR but also didn't have a shot to play this week. He missed practice Wednesday through Friday, allowing Devontae Booker to step in as the lead back -- an assignment he figures to continue this Sunday against the Rams. After that, the Giants face Carolina in Week 7 and Kansas City in Week 8.