Sanders (ankle) wasn't present at practice Wednesday, Josh Tolentino of The Philadelphia Inquirer reports.
Sanders' absence comes as no surprise after head coach Nick Sirianni called Sanders "week to week" Monday as a result of the low-ankle sprain that knocked him out of the Eagles' Week 7 loss at Las Vegas. Sirianni also wouldn't rule Sanders out from making it all the way back to play Sunday in Detroit, leaving the running back with two practices to prove his health. In the event Sanders is sidelined this weekend, he'll yield backfield reps to some combination of Kenneth Gainwell and Boston Scott, while Jordan Howard may also be elevated from the practice squad to bolster the backfield depth.