Pumphrey was limited at Wednesday's practice by a hamstring injury, Dave Zangaro of CSN Philadelphia reports.
Pumphrey was a healthy scratch for Week 1, falling behind LeGarrette Blount, Wendell Smallwood, Darren Sproles and Corey Clement in the running-back pecking order. Barring a Sproles injury, it won't be surprising if the fourth-round rookie is inactive all season, healthy or not.