Ebukam (knee) has been ruled out ahead of Sunday's matchup against the Falcons.
The 30-year-old is now in line to miss his third consecutive game after sustaining an MCL injury in the Week 7 win over the Chargers. With Ebukam and Tyquan Lewis (groin) both sidelined in Week 10, JT Tuimoloau is expected to operate as the Colts' top reserve defensive end.