Mack ran for 89 yards on 12 carries and had a four-yard catch during Sunday's 42-34 loss to the Jets.
The 93 total yards tied a career high for Mack, who was playing his first offensive snaps since Week 2. Trailing by multiple scores early certainly didn't help the Colts stick with the run, but -- provided he's healthy -- Mack looks to be the bell cow in an Indianapolis backfield that struggled mightily in his absence. A Bills defense giving up just 3.8 yards per carry provides a tough next test Sunday.