Mack (foot/hamstring) didn't practice Wednesday, Andrew Walker of the Colts' official site reports.
Mack, who missed time after suffering a hamstring injury in the Colts' first preseason contest, made his season debut last week against Washington, starting at running back and recording 10 carries for 34 yards and one reception for two yards. Per the report, Mack was checked out by team trainers at one point during the Week 2 contest, but was able to return. At this stage, it's expect Mack will be available Sunday against the Eagles, but he'll likely have to share work with Jordan Wilkins and Nyheim Hines.