Downs (knee) didn't practice Thursday, James Boyd of The Athletic reports.
Downs was listed as a non-participant on Wednesday's estimated practice report, so the wideout's continued absence Thursday clouds his availability for Sunday's game against the Patriots. The Colts' final injury report of the week will be released Friday and will add further context regarding Downs' chances of suiting up Sunday. If Downs ends up sitting out, Isaiah McKenzie could be in line for an expanded role at receiver behind Michael Pittman and Alec Pierce.