Head coach Andy Reid said Tuesday that Brown (shoulder) has been ruled out for Thursday's season opener against the Ravens, Pete Sweeney of ArrowheadPride.com reports.
Brown has yet to resume practicing since suffering a left sternoclavicular dislocation Aug. 10, and it never appeared that he had a real chance to be available for Week 1. Reid has now made that official, though he noted that Brown's recovery has been encouraging, per Adam Teicher of ESPN.com. Brown's absence will leave opportunities up for grabs behind TE Travis Kelce and top wideout Rashee Rice. Rookie first-round pick Xavier Worthy could be the biggest beneficiary of extra offensive looks, but all of Justin Watson, JuJu Smith-Schuster, Skyy Moore and Mecole Hardman will be candidates to see increased roles to help cover for Brown's absence.