Head coach Jim Harbaugh said Monday that Njoku will be placed on injured reserve due to a fibula injury, Kris Rhim of ESPN.com reports.
Charlie Kolar (forearm) is also expected to land on IR after both he and Njoku sustained injuries during Sunday's 26-14 loss to the Raiders, with the latter being carted off the field during the second quarter. Njoku is without an official timeline to return, though he won't be eligible to come off IR any earlier than the Chargers' Week 8 matchup with the Rams on Nov. 1. For the time being, second-year pro Oronde Gadsden, who posted a 49-664-3 line on 69 targets across 15 games in 2025, is the only healthy tight end on the Chargers' 53-man roster.