Williams sprained his knee in the Cardinals' Week 5 loss to Philadelphia and isn't expected to play Sunday in Seattle, Ian Rapoport of NFL Network reports.
With Williams and James Conner (ribs) both exiting early in Week 5, Eno Benjamin saw his most extensive NFL action to date out of the backfield, playing 54 percent of the offensive snaps while accounting for 53 yards and a touchdown on 11 touches. The Cardinals signed both Corey Clement and Ty'Son Williams to their practice squad, adding additional depth to their banged-up backfield. Expect at least one to be promoted to the 53-man roster before Sunday, with Williams set to miss the contest and Conner's status for the Week 6 game still uncertain.