Williams carried the ball 14 times for 30 yards and caught his only target for two yards in Sunday's 34-13 loss to the Chargers.
The rookie had reached 80 scrimmage yards or scored a touchdown, or both, in four straight games coming into Sunday, but the knee issue that limited Williams' practice participation during the week may have been a factor in his disappointing showing against one of the league's softer run defenses. He still has an outside chance at 1,000 rushing yards on the season, but he'll need 143 yards in a Week 18 clash with Kansas City to get there.