Gillislee rushed 14 times for 72 yards after replacing an injured LeSean McCoy (thumb) against the Bengals on Sunday.
The Bills relied heavily on the run in a defensive-minded 16-12 victory, even after their starting running back went down. Gillislee served as the workhorse in McCoy's absence, and makes for a strong upside play if McCoy can't return next week against the Bengals. He has averaged 5.8 yards per carry thus far, and still has four touchdowns in the past six games despite not having scored Sunday.