Breida is inactive for Sunday's game against Houston, Chris Brown of the Bills' official site reports.
Breida was given a surprise nod over Zack Moss in the Bils' opener. He didn't do much with the opportunity (four yards on four carries) and wasn't given the ball in Week 2. He's now been made inactive the last two games, meaning his value is shot unless something happens to Moss or Devin Singletary.