Bills head coach Sean McDermott said Friday that Shakir (ankle) won't play Sunday against the Texans.
Shakir, who didn't practice Wednesday or Thursday, thus will target a potential return to action Oct. 14 against the Jets. In Shakir's absence Sunday, Keon Coleman, Mack Hollins, Marquez Valdes-Scantling and Curtis Samuel are on hand to lead Buffalo's wideout corps.