Per Matt Zenitz of CBSSports.com, "there's currently optimism" that Shakir (undisclosed) will be available Week 1 against the Texans on Sunday, Sept. 13
Since making an appearance preseason Week 1 on Aug. 15, Shakir has been sidelined due to an undisclosed injury, including no activity at Tuesday's practice. The Bills will post their first Week 1 injury report next Wednesday, and how he's listed then will provide a sense for his status ahead of the regular-season opener.