Moore did not practice Wednesday due to a quadricep injury.
Moore presumably picked up the quad injury at some point during the Bears' 23-20 loss to the Lions on Thanksgiving Day, though he didn't appear to be laboring at any point during the contest on his way to finishing with a 8-97-1 receiving line on 16 targets. Keenan Allen (ankle) was also sidelined at practice Wednesday, and while it's possible the Bears are simply taking a cautious approach with the health of their top two wideouts, both players' statuses will need to be monitored ahead of Sunday's road matchup against the 49ers. Rookie first-round pick Rome Odunze would step into an increased role on offense if either Moore or Allen are forced to miss any time.