Sermon won't suit up Sunday at the Chargers due to an ankle injury, Nick Wagoner of ESPN.com reports.
The 2021 third-rounder made a surprise appearance on the 49ers' list of players "not expected to play," but an injury and not a coach's decision is forcing the team's hand. Sermon will be unavailable to the backfield along with Raheem Mostert and Elijah Mitchell (hip), meaning San Francisco will trot out Wayne Gallman, JaMycal Hasty, Kyle Juszczyk and Josh Hokit at running back.