Sermon is active for Sunday's game in Philadelphia.
After Sermon was a surprise healthy scratch Week 1, he'll be available to the 49ers backfield Sunday. That said, Elijah Mitchell is expected to be the lead runner in the wake of Raheem Mostert's season-ending knee injury. In the team's season opener at Detroit, Mitchell turned 19 carries into 104 yards and one touchdown, while JaMycal Hasty had two touches for 18 yards and a TD himself. As a result, Sermon may not be available for more than a handful of snaps in the first potential game action of his career.