Sermon (ankle) took part in practice Wednesday, Jennifer Lee Chan of NBC Sports Bay Area reports.
Sermon sat out the team's preseason contest Sunday versus the Chargers while tending to the ankle issue, but he looks to be in good physical condition a few days later. Given his absence from the last preseason contest, there's a chance Sermon is part of the 49ers' backfield mix for the preseason finale Sunday against the Raiders to get him some sort of a tuneup ahead of the regular season.