Mostert won't return to Sunday's game versus the Jets due to a knee injury, Field Yates of ESPN reports.
Mostert went to the locker room early in the first half and didn't return after the break. He was excellent before his departure, totaling 107 yards and a touchdown on 10 touches. For the time being, Tevin Coleman and Jerick McKinnon will handle a bulk of the backfield reps while Jeff Wilson also rotates in.