Breida was a limited practice participant Wednesday with an ankle injury, Cam Inman of The San Jose Mercury News reports.

This is Breida's first appearance on an NFL injury report, coming off a disappointing Week 4 in which he managed just 16 yards on a career-high nine carries. Even if his own injury turns out to be a non-concern, Breida may see his workload reduced Week 5 in Indianapolis, as Carlos Hyde (hip) seemingly avoided any setbacks in last Sunday's 18-15 loss to the Cardinals.