Rourke (ribs) will not return to Thursday night's preseason opener against the Titans, Matt Maiocco of NBC Sports Bay Area reports.
Rourke completed 12 of 14 passes for 101 scoreless yards before suffering a rib injury, allowing Adrian Martinez to come in to finish out the exhibition opener. Rourke also rushed three times for 14 yards prior to his departure. The second-year quarterback's next chance to suit up will be next Thursday against the Chargers.