San Francisco general manager John Lynch said "there's a chance" Wilson (knee) could be activated from the PUP list ahead of Sunday's game against the Cardinals, Matt Barrows of The Athletic reports.
After he was sidelined for the first eight weeks of the season while recovering from late-May surgery to repair a torn meniscus, Wilson was cleared to resume practicing this week. The 49ers will have a 21-day window to evaluate Wilson for a return to the roster, but with Lynch noting that the running back is already back in "tremendous shape," he hasn't been ruled out from making his return to the lineup after just three practices. San Francisco will wait and see how Wilson looks coming out of Friday's session before determining whether to activate him ahead of the 4 p.m. ET deadline Saturday for teams to make Week 9 roster moves.