Wilson (knee) was activated off the PUP list Saturday and will play in Sunday's divisional contest against the Cardinals, Doug Kyed of Pro Football Focus reports.
Wilson was cleared to resume practice this week and the 49ers quickly activated the 25-year-old following a series of solid practices. Clear-cut starter Elijah Mitchell (ribs) is currently listed as questionable for Sunday's pivotal divisional contest, but he did manage to participate in back-to-back practices to close the week. It seems likely the 49ers will ease Wilson back into the fold, particularly given Mitchell's strong play in recent weeks, but it wouldn't be surprising to see the recently activated running back immediately take the change-of-pace carries from Trey Sermon.