Wilson sustained a knee injury during Sunday's loss in Seattle, but he should be able to practice this week, Cam Inman of The San Jose Mercury News reports.
After the game, coach Kyle Shanahan noted Wilson came out of it hobbled but didn't note a body part. On Monday, Shanahan said Wilson's knee "flared up." As a result, Wednesday's injury report will give an indication of his level of health. With Elijah Mitchell and Trenton Cannon in the concussion protocol, the 49ers have just one healthy running back (JaMycal Hasty) on the active roster.