Hasty (ankle) has been ruled out for Sunday's game against the Jaguars, Matt Maiocco of NBC Sports Bay Area reports.
Hasty's absence will create a void in the 49ers' backfield on passing downs, but his status is a secondary concern to that of lead runner Elijah Mitchell (finger), who is listed as doubtful for the contest. In the likely event Mitchell joins Hasty on the 49ers' Week 11 inactive list, the team would be left with Jeff Wilson, Trey Sermon and Trenton Cannon as their available backs, assuming no other additions at the position prior to Sunday's 1 p.m. ET kickoff. Given that neither Sermon nor Cannon has played a snap on offense since Week 5, Wilson could be entrusted with a three-down workhorse role against Jacksonville.