Mitchell (knee) is listed as questionable for Sunday's game against Houston, David Lombardi of The Athletic reports.
Mitchell returned to practice Wednesday as a limited participant and seemingly maintained that level of activity throughout the week without any setbacks, with Nick Wagoner of ESPN.com suggesting the running back is "trending toward being available." On the other hand, Jimmy Garoppolo (hand) is listed as doubtful, leaving Trey Lance as the likely Week 17 starting quarterback. The rookie's previous start came back in Week 5, with Lance taking 16 carries for 89 yards while Mitchell got only 11 touches for 62 yards in the 17-10 loss to Arizona. If he does return this week, Mitchell will get a better matchup with the 49ers being a heavy home favorite against the Texans. If Mitchell is out again, Jeff Wilson presumably will get another week in the lead role.