Mitchell (finger) is listed as inactive Sunday in Jacksonville, Keiana Martin of the 49ers' official site reports.
Mitchell emerged from Week 10 action against the Rams with a broken finger on his right hand that required surgery Tuesday. There was some optimism at the time that the rookie sixth-rounder would be available Sunday, but Mitchell didn't practice Wednesday through Friday and entered the weekend as doubtful to suit up. With his status for Week 11 now confirmed, the 49ers backfield will be down both Mitchell and JaMycal Hasty (ankle), leaving Jeff Wilson, Trey Sermon, Trenton Cannon and Kyle Juszczyk as the team's options at running back.