Samuel is tending to an illness but is expected to play Sunday against the Chiefs, Matt Maiocco of NBC Sports Bay Area reports.
Samuel operated with a cap on his reps this past week due to a wrist injury but ultimately was cleared to suit up for Week 7 action. With an ailment now in tow, there's a chance his snap share is below its norm of 70-plus percent, which could open up reps for Brandon Aiyuk, Ricky Pearsall and Chris Conley, with Jauan Jennings (hip) sidelined.