Chisholm has been placed in concussion protocol after exiting Monday's game against the Tigers in the fourth inning following a collision with teammate Jasson Dominguez.
Chisholm will need to pass through the league's concussion protocol before returning to the diamond. Amed Rosario and Jose Caballero are the top two candidates to see playing time at second base until Chisholm is cleared to return, though Oswaldo Cabrera could also factor into the mix.