Weissert was optioned to Triple-A Scranton/Wilkes-Barre following Tuesday's 10-5 win over the Athletics.
Weissert was with the Yankees for only one day after being called up from Triple-A on Tuesday, and he allowed two runs over an inning of relief with a walk and two strikeouts in his lone appearance. The Yankees will announce a corresponding move prior to Wednesday's series finale with Oakland.