White Sox manager Tony La Russa said Lopez will start Saturday's game against the Royals, Daryl Van Schouwen of the Chicago Sun-Times reports.
After striking out seven in five perfect frames last Friday against the Cubs in his return to the bullpen, Lopez will step back into the rotation during the upcoming weekend as a replacement for Lance Lynn (knee), who was placed on the injured list Tuesday. Lynn is only expected to miss one turn through the rotation, but Lopez could have the opportunity to pick up another start after Saturday if Lucas Giolito is slow to recover from the hamstring injury he sustained Tuesday.