Jeffers was placed on the 10-day injured list Friday with a right thumb contusion.
Jeffers presumably picked up the injury during Thursday's matchup with the White Sox, when he went 1-for-4 with a strikeout. According to Aaron Gleeman of The Athletic, manager Rocco Baldelli believes the injury is more serious than a typical contusion, so the 25-year-old may be sidelined beyond the 10-day minumum. Gary Sanchez should operate as Minnesota's primary catcher in the meantime, while Caleb Hamilton was called up to fill backup duties.