The Twins placed Hoffman on the 15-day injured list Saturday with right forearm inflammation, Aaron Gleeman of AaronGleeman.com reports.
Hoffman's forearm injury will cause his season to end a few days early, and he'll finish the year with a 3.55 ERA and 1.32 WHIP over 66 innings between Toronto and Minnesota. He also recorded six saves and a career-high 22 holds. His roster spot will be given to Kaelen Culpepper (hamstring), who was reinstated from the 10-day IL in a corresponding move.