Castro was recalled from Triple-A Toledo ahead of Tuesday's game against the Rays.
Castro appears to be over a minor oblique issue that kept him out of the big leagues near the end of May when the Tigers needed a middle infielder, so he'll replace Jeimer Candelario (shoulder), who was moved to the 10-day injured list Tuesday. Castro is 5-for-22 with a double over nine games this year with Detroit.